Vacuum Pumps for the Pharmaceutical Industry

Vacuum pumps in pharmaceutical industries are extensively used at all levels of production, whether it be bulk manufacturing, intermediate production, or production of active pharmaceutical ingredients (API).

The typical applications for which vacuum pumps are widely used are listed below:

Degassing

The process of removing dissolved gasses from liquids or solids is known as degassing. Vacuum pumps help to degass products by reducing pressure.

Vacuum Distillation

Distillation is a process used to purify compounds by separating solvents. Vacuum distillation uses vacuum systems that reduce pressure for purification. Vacuum distillation saves both time and energy.

Crystallization

Crystallization is the process of forming crystals. Supersaturated liquids are first evaporated and then cooled down to form crystals. Vacuum pumps control the rate of evaporation and cooling.

Drying

The process is used to remove moisture from solids by heating them. A vacuum is created for the process to maintain low temperatures. The process is usually used for hygroscopic substances or for substances that are sensitive to heat. 

Freeze Drying

Freeze drying is the process of removing water at low temperatures. The process works by first freezing the material, then allowing the water (ice) to sublime, i.e. directly covert into water vapors without going through the liquefaction phase. Pharmaceutical companies use the process for extending the shelf life of the product. A vacuum system is used to remove the moisture.

Sterilization

Sterilization is an effective method used to eliminate microbes and organisms. The most used sterilization methods are Steam Sterilization and Ethylene Oxide (ETO) sterilization. The evacuation of the sterilization chamber is done by a vacuum pump.

Steam Sterilization and Ethylene Oxide Sterilization (ETO)

Steam sterilization is the most popular and most efficient method of sterilization. It uses high temperatures and high pressures to kill all the microorganisms. The autoclave is filled with steam and is allowed to elevate temperature. Once the sterilization occurs, the drying cycle takes place. The vacuum system should be efficient enough to carry out the entire process.

Ethylene oxide (ETO) sterilization is a very cost-effective method of sterilization. It is a low-temperature sterilization method. The process requires either 100% ethylene oxide or a premix blend ethylene oxide and an inert gas. The process of using 100 % ethylene oxide requires a vacuum.

The first stage is preconditioning in which temperature and humidity of the load should be raised. The load is then transferred to a sterilization chamber where a vacuum is pulled to remove the air. The conditioning phase takes place at optimum humidity. ETO is then introduced in the chamber and is allowed to soak into the load until the sterility assurance level is achieved. ETO is then removed through vacuums and washes.

Economy Vacuum Systems

Economy Vacuum Systems offer trouble-free vacuum solutions and products that fulfill customer’s preferences. The vacuum pump used for the processes is selected from our wide range encompassing:

  1. Liquid Ring Vacuum Pump is designed for optimum effectiveness with a full sealant recirculation system. Sealant selection can be from water, oil, solvent, etc. depending on the application.
  2. Dry Screw Vacuum Pump with vertical discharge and built to handle corrosive and abrasive vapors at high operating temperatures.
  3. Hook and Claw Dry Pump in air-cooled and water-cooled options offer a low-cost reliable alternative to applications where water ring vacuum pumps are currently used. Huge advantage is the 50% reduction in power requirement when compared to a water ring vacuum pump.
  4. Oil Sealed Rotary Pump is a single or double stage vane pump which is an economical solution for relatively clean applications requiring high vacuum
  5. Rotary Piston Pump is a rugged pump for high vacuum applications.
  6. Vacuum Boosters with twin lobe design can be packaged with any primary vacuum device to boost capacity and vacuum levels at very low costs and low power requirements.

Our customized engineered solutions are offered for various applications drawing on our experience of supplying several thousand systems worldwide.

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